Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GCKR | Q14397 | 10/20 | 0.38 |
| ▸ | GCK | P35557 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055263 | 0.74 | DRD2 (0.42) | CHRNB2CHRNA4GCKRGCKDRD2 | |
| SCHEMBL28055261 | 0.74 | DRD2 (0.42) | CHRNB2CHRNA4GCKRGCKDRD2 | |
| SCHEMBL22650580 | 0.73 | CHRNB2 (0.52) | CHRNB2CHRNA4GCKRDRD2DRD3 | |
| SCHEMBL14916285 | 0.69 | CHRNB2 (0.41) | CHRNB2CHRNA4GCKRGCKPIK3CA | |
| SCHEMBL23089144 | 0.69 | CHRNB2 (0.44) | CHRNB2CHRNA4GCKRGCKDRD2 | |
| SCHEMBL21275464 | 0.69 | CHRNB2 (0.44) | CHRNB2CHRNA4GCKRGCKPIK3CA | |
| SCHEMBL29814518 | 0.69 | CHRNB2 (0.44) | CHRNB2CHRNA4GCKRGCKDRD2 | |
| SCHEMBL23104482 | 0.69 | CHRNB2 (0.44) | CHRNB2CHRNA4GCKRGCKDRD2 | |
| SCHEMBL30664067 | 0.68 | GAA (0.62) | GCKRGCK | |
| SCHEMBL611882 | 0.68 | GAA (0.62) | GCKRGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |