Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650721 | 0.83 | SMN1; SMN2 (0.34) | ALDH1A1HTTGAA | |
| SCHEMBL22650586 | 0.76 | EGFR (0.39) | — | |
| SCHEMBL22650358 | 0.74 | EGFR (0.33) | ALDH1A1GAA | |
| SCHEMBL22650399 | 0.70 | CDK4 (0.33) | ALDH1A1GAA | |
| SCHEMBL22650372 | 0.68 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL30838827 | 0.67 | PIK3CA (0.46) | ALDH1A1HTTGAAGRM2POLB | |
| SCHEMBL17364311 | 0.67 | CDK1 (0.46) | YTHDC1 | |
| SCHEMBL29235905 | 0.67 | PIK3CA (0.46) | ALDH1A1HTTGAAGRM2POLB | |
| SCHEMBL24054074 | 0.66 | ALDH1A1 (0.36) | ALDH1A1HTTGAAPOLBCASP6 | |
| SCHEMBL30166276 | 0.66 | ALDH1A1 (0.36) | ALDH1A1HTTGAAPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |