Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 6/20 | 0.31 |
| ▸ | CCND1 | P24385 | 6/20 | 0.31 |
| ▸ | CCND3 | P30281 | 5/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650372 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL22650727 | 0.83 | ALDH1A1 (0.33) | ALDH1A1HTTGAA | |
| SCHEMBL22650586 | 0.81 | EGFR (0.39) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL22650407 | 0.78 | L3MBTL1 (0.37) | SMN1; SMN2L3MBTL1CCNA2CDK2CCNA1 | |
| SCHEMBL24632941 | 0.78 | CDK4 (0.43) | SMN1; SMN2CCNA2CDK2CDK4CCND1 | |
| SCHEMBL22650364 | 0.77 | CDK4 (0.37) | SMN1; SMN2CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL22650360 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CCNA2CDK2CCNA1 | |
| SCHEMBL22650358 | 0.75 | EGFR (0.33) | ALDH1A1GAACCNA2CDK2CDK4 | |
| SCHEMBL30888943 | 0.72 | CDK4 (0.50) | CCNA2CDK2CDK4CCND1CCND3 | |
| SCHEMBL27445903 | 0.70 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |