Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.40 |
| ▸ | FEN1 | P39748 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 2/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037438 | 0.85 | HRH3 (0.45) | ALOX5APFEN1HRH3CHRNB2CHRNA4 | |
| SCHEMBL20037834 | 0.84 | DRD3 (0.40) | HRH3CHRNB2CHRNA4AKR1C3PIK3CA | |
| SCHEMBL18291570 | 0.84 | HRH3 (0.39) | HRH3AKR1C3ALDH1A1 | |
| SCHEMBL20037471 | 0.84 | HRH3 (0.39) | HRH3AKR1C3ALDH1A1 | |
| SCHEMBL20249378 | 0.81 | HSD11B1 (0.37) | HRH3AKR1C3PIK3CAMTOR | |
| SCHEMBL20249119 | 0.81 | HSD11B1 (0.37) | HRH3AKR1C3PIK3CAMTOR | |
| SCHEMBL22650368 | 0.79 | ALOX5AP (0.37) | ALOX5APFEN1CHRNB2CHRNA4AKR1C3 | |
| SCHEMBL29462389 | 0.79 | ALOX5AP (0.37) | ALOX5APFEN1CHRNB2CHRNA4AKR1C3 | |
| SCHEMBL22650819 | 0.79 | HRH3 (0.39) | HRH3CHRNB2CHRNA4AKR1C3 | |
| SCHEMBL22650820 | 0.78 | CHRNB2 (0.34) | ALOX5APFEN1HRH3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |