Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15566847 | 0.87 | GPR119 (0.48) | BACE1KDM4EPKMGPR119MAPT | |
| SCHEMBL31108104 | 0.86 | FPR2 (0.51) | BACE1KDM4EPKMGPR119MAPT | |
| SCHEMBL27077258 | 0.84 | KDM4E (0.52) | BACE1KDM4EPKMGPR119 | |
| SCHEMBL3505577 | 0.84 | BACE1 (0.46) | BACE1KDM4EPKMGPR119NR1H2 | |
| SCHEMBL28402009 | 0.82 | BACE1 (0.51) | BACE1KDM4EPKMGPR119MAPT | |
| SCHEMBL31630958 | 0.81 | KDM4E (0.48) | BACE1KDM4EPKMGPR119MAPT | |
| SCHEMBL21245743 | 0.80 | GPR119 (0.48) | BACE1KDM4EGPR119MAPTTHRB | |
| SCHEMBL31108111 | 0.80 | IDO1 (0.46) | KDM4EPKMGPR119MAPTTHRB | |
| SCHEMBL28397415 | 0.79 | KDM4E (0.52) | BACE1KDM4EPKMGPR119MAPT | |
| SCHEMBL7808872 | 0.78 | NR1H2 (0.44) | BACE1KDM4EPKMGPR119NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |