Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650836 | 0.82 | BACE1 (0.48) | BACE1KDM4EPKMFPR2GPR119 | |
| SCHEMBL28398159 | 0.81 | BACE1 (0.50) | BACE1KDM4EPKMFPR2GPR119 | |
| SCHEMBL28398168 | 0.80 | BACE1 (0.49) | BACE1KDM4EPKMFPR2GPR119 | |
| SCHEMBL3505577 | 0.79 | BACE1 (0.46) | BACE1KDM4EPKMGPR119TGFBR1 | |
| SCHEMBL4777921 | 0.79 | KDM4E (0.54) | KDM4EPKMGPR119 | |
| SCHEMBL28397415 | 0.79 | KDM4E (0.52) | BACE1KDM4EPKMFPR2GPR119 | |
| SCHEMBL31630958 | 0.79 | KDM4E (0.48) | BACE1KDM4EPKMFPR2GPR119 | |
| SCHEMBL17394747 | 0.79 | BACE1 (0.47) | BACE1KDM4EPKMGPR119CTSD | |
| SCHEMBL15566847 | 0.78 | GPR119 (0.48) | BACE1KDM4EPKMFPR2GPR119 | |
| SCHEMBL1589991 | 0.78 | BACE1 (0.47) | BACE1KDM4EPKMFPR2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883217-B | Nucleoside base hydroxamic acid derivative compound and preparation method and application thereof | 清华大学深圳研究生院 | 2020-05-22 | — | — | CN | disclosed |