Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651449 | 0.83 | HSD11B1 (0.48) | L3MBTL3L3MBTL1HSD11B1KDM1A | |
| SCHEMBL15651448 | 0.83 | HSD11B1 (0.48) | L3MBTL3L3MBTL1HSD11B1KDM1A | |
| SCHEMBL2887251 | 0.81 | L3MBTL3 (0.69) | L3MBTL3PDK2ATRL3MBTL1HRH3 | |
| SCHEMBL22165523 | 0.81 | L3MBTL3 (0.69) | L3MBTL3PDK2ATRL3MBTL1HRH3 | |
| SCHEMBL24185218 | 0.81 | L3MBTL3 (0.69) | L3MBTL3PDK2ATRL3MBTL1HRH3 | |
| SCHEMBL19321958 | 0.79 | ALDH1A1 (0.63) | L3MBTL3PDK2HTR7L3MBTL1HRH3 | |
| SCHEMBL2987028 | 0.79 | L3MBTL3 (0.69) | L3MBTL3PDK2ATRL3MBTL1HRH3 | |
| SCHEMBL13451259 | 0.79 | HSD11B1 (0.52) | L3MBTL3HTR7L3MBTL1HSD11B1KDM1A | |
| SCHEMBL22164624 | 0.78 | ATR (0.52) | L3MBTL3PDK2ATRMAP4K4 | |
| SCHEMBL22164625 | 0.78 | ATR (0.52) | L3MBTL3PDK2ATRMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |