SCHEMBL22650970

SCHEMBL22650970

Clc1cc(-c2ccccc2)c2cc3ccccc3cc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.50
ESR2 Q92731 6/20 0.50
MAPT P10636 3/20 0.46
MAPK1 P28482 1/20 0.45
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 1/20 0.41
MPI P34949 1/20 0.41
ELANE P08246 1/20 0.40
LMNA P02545 2/20 0.40
ACACA Q13085 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4083079 0.83 ACACA (0.50) MAPTMAPK1KDM4EMEN1ALDH1A1
SCHEMBL29352882 0.83 ACACA (0.50) MAPTMAPK1KDM4EMEN1ALDH1A1
SCHEMBL11826284 0.82 MAPK1 (0.65) MAPTMAPK1AURKAAURKBTP53
SCHEMBL28181895 0.82 PIK3CA (0.51) ESR1ESR2MAPTMAPK1AURKA
SCHEMBL13376535 0.81 TP53 (0.59) ESR1ESR2MAPTMAPK1AURKA
SCHEMBL17508350 0.80 ACACA (0.51) MAPTMAPK1AURKAAURKBKDM4E
SCHEMBL23674184 0.79 MAPK1 (0.47) ESR1ESR2MAPTMAPK1AURKA
SCHEMBL11827110 0.79 MAPK1 (0.47) ESR1ESR2MAPTMAPK1AURKA
SCHEMBL2891921 0.79 PRNP (0.47) MAPTMAPK1AURKAAURKBMEN1
SCHEMBL23674185 0.79 ESR2 (0.56) ESR1ESR2MAPTMAPK1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020226295-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-11-12 WO disclosed