SCHEMBL4083079

SCHEMBL4083079

Clc1cc(-c2ccccc2)c2ccccc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 4/20 0.50
EGFR P00533 1/20 0.50
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
KDM4E B2RXH2 5/20 0.46
MAPK1 P28482 2/20 0.45
USP2 O75604 1/20 0.45
HTT P42858 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
MPI P34949 1/20 0.44
KMT2A Q03164 1/20 0.44
ELANE P08246 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352882 1.00 ACACA (0.50) ACACAEGFRMAOAMAOBKDM4E
SCHEMBL17508350 0.96 ACACA (0.51) ACACAEGFRMAOAMAOBKDM4E
SCHEMBL10629041 0.91 LTB4R (0.50) ACACAMAOAMAOBKDM4EMAPK1
SCHEMBL17508372 0.89 MAOA (0.42) ACACAEGFRMAOAMAOBKDM4E
SCHEMBL10630879 0.88 GRM2 (0.58) ACACAMAOAMAOBKDM4EALDH1A1
SCHEMBL10627563 0.88 ALDH1A1 (0.55) ACACAKDM4EHTTALDH1A1HPGD
SCHEMBL17508354 0.84 GSTP1 (0.46) ACACAMAOAMAOBKDM4EUSP2
SCHEMBL10627554 0.84 LTB4R (0.51) ACACA
SCHEMBL22650970 0.83 ESR1 (0.50) ACACAKDM4EMAPK1ALDH1A1HPGD
SCHEMBL11826284 0.83 MAPK1 (0.65) ACACAKDM4EMAPK1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105198806-A Method for synthesizing quinoline by aromatic amine and diketone UNIV NANYANG NORMAL 2015-12-30 CN claimed
CN-103467447-B One class electroluminescent organic material and applying in the devices Jilin Optical and Electronic Materials Co., Ltd. (CN) 2015-10-28 CN claimed
CN-103467447-A Novel organic electroluminescent (EL) material and application thereof in devices JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD 2013-12-25 CN claimed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11527723-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-12-13 US disclosed
WO-2022239930-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE 엘티소재주식회사 2022-11-17 WO disclosed
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element LT MATERIALS CO., LTD. (KR) 2022-07-12 US disclosed
EP-3604298-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO LTD (KR) 2022-03-30 EP disclosed
US-11208401-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-12-28 US disclosed
US-11201296-B2 Compounds having fluorene structures MERCK PATENT GMBH (DE) 2021-12-14 US disclosed
EP-0210084-B1 AMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM RHONE-POULENC SANTE (FR) 1989-02-08 EP disclosed
US-4788204-A TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS RHONE-POULENC SANTE (FR) 1988-11-29 US disclosed
US-4788199-A ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS RHONE-POULENC SANTE (FR) 1988-11-29 US disclosed
US-4677107-A 2-PIPERAZINYL-4-PHENYLQUINOLINES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1987-06-30 US disclosed
EP-0210084-A1 Amides, processes for their preparation and medicaments containing them RHONE-POULENC SANTE (FR) 1987-01-28 EP disclosed
EP-0127189-A2 Anti-peptic ulcer agent Dainippon Pharmaceutical Co., Ltd. (JP) 1984-12-05 EP disclosed
US-4237135-A ANTIDEPRESSANTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1980-12-02 US disclosed
US-4000151-A TRANQUILIZERS, SEDATIVES THE UPJOHN COMPANY (US) 1976-12-28 US disclosed
US-4000153-A TRANQUILIZERS, SEDATIVES THE UPJOHN COMPANY (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element CRY1, CYBA, L1CAM ACACA 3523/4885EGFR 3820/4885MAOA 121/4885
US-11208401-B2 Materials for organic electroluminescent devices DDT, CELF2, BRD3 ACACA 3634/4885EGFR 2517/4885MAOA 1116/4885
US-11201296-B2 Compounds having fluorene structures FSCN1, EFNA1, FLNA ACACA 3682/4885EGFR 1741/4885MAOA 695/4885
US-11527723-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 ACACA 2714/4885EGFR 2783/4885MAOA 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.