Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 4/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352882 | 0.96 | ACACA (0.50) | ACACAEGFRMAOAMAOBKDM4E | |
| SCHEMBL4083079 | 0.96 | ACACA (0.50) | ACACAEGFRMAOAMAOBKDM4E | |
| SCHEMBL10629041 | 0.91 | LTB4R (0.50) | ACACAMAOAMAOBKDM4EMAPK1 | |
| SCHEMBL17508372 | 0.89 | MAOA (0.42) | ACACAEGFRMAOAMAOBKDM4E | |
| SCHEMBL10630879 | 0.88 | GRM2 (0.58) | ACACAMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL10627563 | 0.88 | ALDH1A1 (0.55) | ACACAKDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL28181895 | 0.87 | PIK3CA (0.51) | ACACAKDM4EMAPK1ALDH1A1MAPT | |
| SCHEMBL17508354 | 0.84 | GSTP1 (0.46) | ACACAMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL10627554 | 0.84 | LTB4R (0.51) | ACACAGRM2 | |
| SCHEMBL4607752 | 0.81 | ACACA (0.73) | ACACAKDM4EMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | AHR, CDYL, SLC18A1 | ACACA 3729/4885EGFR 1935/4885MAOA 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.