Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.64 |
| ▸ | WNT3A | P56704 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627847 | 0.89 | ATM (0.70) | CTNNB1WNT3AALDH1A1MAPK1HPGD | |
| SCHEMBL22651304 | 0.86 | CTNNB1 (0.69) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL2985748 | 0.86 | ALDH1A1 (0.68) | CTNNB1WNT3AALDH1A1KMT2AHPGD | |
| SCHEMBL2237626 | 0.85 | MEN1 (0.76) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL29458253 | 0.85 | MEN1 (0.76) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL6486626 | 0.84 | CTNNB1 (0.66) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL4865452 | 0.84 | CTNNB1 (0.66) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL7385092 | 0.82 | ALDH1A1 (0.64) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL2843731 | 0.82 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL4258312 | 0.82 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704105-B9 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD (GB) | 2025-03-05 | — | — | EP | disclosed |
| EP-3704105-B1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD (GB) | 2024-10-16 | — | — | EP | disclosed |
| EP-4368184-A2 | NOVEL COMPOUNDS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH THE AGGREGATION OF ALPHA-SYNUCLEIN | Modag GmbH (DE) | 2024-05-15 | — | — | EP | disclosed |
| US-11680062-B2 | 3,4-methylenedioxyphenylimidazolylethanonexime ether derivative, preparation method and use thereof, and drug for the treatment of Alzheimer's disease | NORTHWEST A & F UNIVERSITY (CN) | 2023-06-20 | — | — | US | disclosed |
| US-11680062-B2 | 3,4-methylenedioxyphenylimidazolylethanonexime ether derivative, preparation method and use thereof, and drug for the treatment of Alzheimer's disease | NORTHWEST A & F UNIVERSITY (CN) | 2023-06-20 | — | — | US | disclosed |
| US-11680062-B2 | 3,4-methylenedioxyphenylimidazolylethanonexime ether derivative, preparation method and use thereof, and drug for the treatment of Alzheimer's disease | NORTHWEST A & F UNIVERSITY (CN) | 2023-06-20 | — | — | US | disclosed |
| US-20230159503-A1 | 3,4-METHYLENEDIOXYPHENYLIMIDAZOLYLETHANONEXIME ETHER DERIVATIVE, PREPARATION METHOD AND USE THEREOF, AND DRUG FOR THE TREATMENT OF ALZHEIMER'S DISEASE | NORTHWEST A & F UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159503-A1 | 3,4-METHYLENEDIOXYPHENYLIMIDAZOLYLETHANONEXIME ETHER DERIVATIVE, PREPARATION METHOD AND USE THEREOF, AND DRUG FOR THE TREATMENT OF ALZHEIMER'S DISEASE | NORTHWEST A & F UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159503-A1 | 3,4-METHYLENEDIOXYPHENYLIMIDAZOLYLETHANONEXIME ETHER DERIVATIVE, PREPARATION METHOD AND USE THEREOF, AND DRUG FOR THE TREATMENT OF ALZHEIMER'S DISEASE | NORTHWEST A & F UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230067910-A1 | NOVEL COMPOUNDS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH THE AGGREGATION OF ALPHA-SYNUCLEIN | MODAG GMBH (DE) | 2023-03-02 | — | — | US | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0350251-B1 | N-Substituted amide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4937360-A | N-substituted amide derivatives useful for treating liver diseases | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-26 | — | — | US | disclosed |
| EP-0350251-A2 | N-Substituted amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4684739-A | HYPOTENSIVE AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0054304-B1 | ALKYLENEDIOXYBENZENE DERIVATIVES, ACID ADDITION SALTS THEREOF AND A METHOD FOR THEIR PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1984-08-15 | — | — | EP | disclosed |
| US-4446141-A | Hypotensive piperidine derivatives | KYOWA HAKKO KOGYO CO. (JP) | 1984-05-01 | — | — | US | disclosed |
| EP-0018417-B1 | NOVEL PIPERIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1982-06-30 | — | — | EP | disclosed |
| EP-0018417-A1 | Novel piperidine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1980-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230067910-A1 | NOVEL COMPOUNDS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH THE AGGREGATION OF ALPHA-SYNUCLEIN | SNCA, PARK7, SYNCRIP | CTNNB1 2069/4885WNT3A 2822/4885ALDH1A1 950/4885 |
| US-20230159503-A1 | 3,4-METHYLENEDIOXYPHENYLIMIDAZOLYLETHANONEXIME ETHER DERIVATIVE, PREPARATION METHOD AND USE THEREOF, AND DRUG FOR THE TREATMENT OF ALZHEIMER'S DISEASE | NOS3, CYP51A1, NOS1 | CTNNB1 2714/4885WNT3A 588/4885ALDH1A1 1852/4885 |
| US-11680062-B2 | 3,4-methylenedioxyphenylimidazolylethanonexime ether derivative, preparation method and use thereof, and drug for the treatment of Alzheimer's disease | NOS3, CYP51A1, NOS1 | CTNNB1 2714/4885WNT3A 588/4885ALDH1A1 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.