SCHEMBL22651727

SCHEMBL22651727

CCCCCCCCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1O)c64)C(=O)N(CC)C5=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ TERT O14746 4/20 0.40
▸ KDM4E B2RXH2 3/20 0.40
▸ POLB P06746 2/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ KMT2A Q03164 4/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ CYP1B1 Q16678 3/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ LMNA P02545 3/20 0.39
▸ USP2 O75604 2/20 0.39
▸ ATM Q13315 2/20 0.39
▸ KEAP1 Q14145 1/20 0.39
▸ NFE2L2 Q16236 1/20 0.39
▸ HTT P42858 3/20 0.38
▸ RGS12 O14924 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ PABPC1 P11940 1/20 0.38
▸ RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20392828 0.94 STAT3 (0.48) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL23987286 0.89 HEXA (0.44) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL22651618 0.84 STAT3 (0.39) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL23957124 0.84 HDAC3 (0.35) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL22651696 0.83 KDM4E (0.36) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL22651728 0.83 KDM4E (0.36) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL24017161 0.82 MEN1 (0.38) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL23425474 0.82 TERT (0.40) TERTKDM4EKMT2AALDH1A1MEN1
SCHEMBL18379126 0.81 STAT3 (0.60) STAT3HIF1ATERTKDM4EPOLB
SCHEMBL19019036 0.81 CYP1B1 (0.49) TERTKDM4EPOLBALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2020-11-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 STAT3 4101/4885HIF1A 3544/4885TERT 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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