SCHEMBL22651618

SCHEMBL22651618

CCCCCCCCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1O)c64)C(=O)N(Cc1ccc(N(C)C)cc1)C5=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ CLTC Q00610 1/20 0.38
▸ TERT O14746 4/20 0.38
▸ FGFR1 P11362 2/20 0.35
▸ KDR P35968 2/20 0.35
▸ PDGFRA P16234 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ KDM4E B2RXH2 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ RGS12 O14924 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ RECQL P46063 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23957124 0.87 HDAC3 (0.35) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18379167 0.85 STAT3 (0.54) STAT3HIF1ACLTCTERTFGFR1
SCHEMBL20392828 0.85 STAT3 (0.48) STAT3HIF1ATERTFGFR1KDR
SCHEMBL23425474 0.85 TERT (0.40) TERTKDM4EMEN1KMT2AMAPT
SCHEMBL22651727 0.84 STAT3 (0.41) STAT3HIF1ATERTFGFR1KDR
SCHEMBL23425475 0.83 HDAC6 (0.43) TERTHPGDKDM4EMEN1KMT2A
SCHEMBL23987286 0.81 HEXA (0.44) STAT3HIF1ATERTFGFR1KDR
SCHEMBL22651653 0.80 STAT3 (0.37) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18379202 0.77 STAT3 (0.41) STAT3HIF1ACLTCTERTFGFR1
SCHEMBL18379136 0.75 STAT3 (0.50) STAT3HIF1ATERTFGFR1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2020-11-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 STAT3 4101/4885HIF1A 3544/4885CLTC 2708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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