SCHEMBL226524

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL227769	0.82	OPRK1 (0.57)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL6420508	0.80	DRD2 (0.45)	DRD2DRD1OPRK1DRD3CYP3A4
	SCHEMBL225057	0.77	DRD2 (0.49)	DRD2DRD1OPRK1DRD3ESR2
	SCHEMBL31187229	0.76	OPRK1 (0.50)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL223902	0.73	ESR1 (0.52)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL29791484	0.73	ESR1 (0.52)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL22355540	0.73	ESR1 (0.52)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL30616504	0.73	ESR1 (0.52)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL224545	0.73	CYP26A1 (0.50)	DRD2OPRK1DRD3ESR2ESR1
	SCHEMBL1344597	0.70	OPRK1 (0.59)	DRD2OPRK1DRD3ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.