Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 14/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654073 | 0.83 | GRM4 (0.38) | GRM4LMNACDK8ACVR1 | |
| SCHEMBL22654078 | 0.80 | GAA (0.34) | GRM4LMNACDK8ACVR1TRPV3 | |
| SCHEMBL28444233 | 0.78 | GRM4 (0.36) | GRM4CDK8ACVR1 | |
| SCHEMBL30389348 | 0.75 | NR3C1 (0.34) | GRM4TRPV3MAPT | |
| SCHEMBL25180896 | 0.75 | NR3C1 (0.34) | GRM4TRPV3MAPT | |
| SCHEMBL30388670 | 0.72 | CYP1A2 (0.33) | TRPV3 | |
| SCHEMBL25180330 | 0.72 | CYP1A2 (0.33) | TRPV3 | |
| SCHEMBL29263842 | 0.72 | GRM4 (0.33) | GRM4 | |
| SCHEMBL29263850 | 0.65 | LMNA (0.35) | LMNACDK8ACVR1KMT2AMAPT | |
| SCHEMBL22031792 | 0.65 | CASR (0.40) | LMNACDK8ACVR1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737667-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-11-18 | — | — | EP | disclosed |