Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224619 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL17207273 | 0.77 | BCHE (0.34) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL271027 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL74779 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL221749 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL11791908 | 0.76 | PTPN1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL17880417 | 0.76 | PTPN1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL11791904 | 0.76 | PTPN1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL13738588 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL31298510 | 0.76 | PTPN1 (0.38) | ALDH1A1LMNAHSD17B10TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746452-B1 | STEREOSELECTIVE SYNTHESIS AND PROCESS FOR THE MANUFACTURING OF 2'-DEOXYNUCLEOSIDES | US HEALTH (US) | 2023-09-13 | — | — | EP | disclosed |
| US-11365211-B2 | Stereoselective synthesis and process for the manufacturing of 2′-deoxynucleosides | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-06-21 | — | — | US | disclosed |
| US-20200361977-A1 | STEREOSELECTIVE SYNTHESIS AND PROCESS FOR THE MANUFACTURING OF 2'-DEOXYNUCLEOSIDES | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365211-B2 | Stereoselective synthesis and process for the manufacturing of 2′-deoxynucleosides | DCTD, DUT, TET1 | ALDH1A1 612/4885LMNA 3351/4885HSD17B10 1786/4885 |
| US-20200361977-A1 | STEREOSELECTIVE SYNTHESIS AND PROCESS FOR THE MANUFACTURING OF 2'-DEOXYNUCLEOSIDES | DCTD, DUT, TET1 | ALDH1A1 612/4885LMNA 3378/4885HSD17B10 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.