Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412250 | 0.66 | THRB (0.40) | THRB | |
| SCHEMBL224287 | 0.66 | THRB (0.40) | THRB | |
| SCHEMBL441769 | 0.64 | THRB (0.38) | THRB | |
| SCHEMBL29883163 | 0.64 | THRB (0.38) | THRB | |
| SCHEMBL3558295 | 0.63 | — | — | |
| SCHEMBL11252538 | 0.62 | LMNA (0.41) | THRB | |
| SCHEMBL9138516 | 0.62 | THRB (0.36) | THRB | |
| SCHEMBL11260144 | 0.61 | THRB (0.35) | THRB | |
| SCHEMBL27803886 | 0.59 | THRB (0.44) | THRB | |
| SCHEMBL289118 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994168-B2 | Hexahydro-pyrazino[1,2-A]pyrimidine-4,7-dione derivatives substituted with amino acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-08-09 | — | — | US | disclosed |