Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15120497 | 0.87 | THRB (0.35) | THRBLMNA | |
| SCHEMBL8066288 | 0.86 | LMNA (0.36) | THRBLMNA | |
| SCHEMBL11273688 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL15121222 | 0.83 | LMNA (0.36) | THRBLMNA | |
| SCHEMBL412250 | 0.82 | THRB (0.40) | THRBLMNA | |
| SCHEMBL9138516 | 0.78 | THRB (0.36) | THRBLMNA | |
| SCHEMBL1097900 | 0.77 | — | — | |
| SCHEMBL441769 | 0.74 | THRB (0.38) | THRBLMNA | |
| SCHEMBL18762321 | 0.74 | THRB (0.33) | THRBLMNA | |
| SCHEMBL24777179 | 0.72 | THRB (0.36) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912790-B | Polymer microsphere and preparation method and application thereof | 烟台明远创意生活科技股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-107488171-B | Preparation method of afatinib | 山东新时代药业有限公司 | 2020-08-28 | — | — | CN | claimed |
| CN-107488153-B | Afatinib intermediate compound | 山东新时代药业有限公司 | 2020-06-23 | — | — | CN | claimed |
| EP-2245132-B1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC NO 41424 (GB) | 2017-10-18 | — | — | EP | claimed |
| US-9758471-B2 | Process for the preparation of 4-dimethylaminocrotonic acid | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2017-09-12 | — | — | US | claimed |
| US-20170107172-A1 | PROCESS FOR THE PREPARATION OF 4-DIMETHYLAMINOCROTONIC ACID | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2017-04-20 | — | — | US | claimed |
| EP-3148977-A1 | PROCESS FOR THE PREPARATION OF 4-DIMETHYLAMINOCROTONIC ACID | Sun Pharmaceutical Industries Ltd (IN) | 2017-04-05 | — | — | EP | claimed |
| WO-2015186065-A1 | PROCESS FOR THE PREPARATION OF 4-DIMETHYLAMINOCROTONIC ACID | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2015-12-10 | — | — | WO | claimed |
| CN-104529800-A | Preparation method of trans-4-dimethylaminocrotonic acid and its salt | CHONGQING WEIPENG PHARMACEUTICAL CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-102015993-B | Encapsulated benefit agent | UNILEVER PLC | 2013-03-27 | — | — | CN | claimed |
| EP-2245132-A1 | ENCAPSULATED BENEFIT AGENT | Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) | 2010-11-03 | — | — | EP | claimed |
| WO-2009103576-A1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC (GB) | 2009-08-27 | — | — | WO | claimed |
| US-4983748-A | Chemical intermediates for polysaccharide aldehydes; wet strength paper additive | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-01-08 | — | — | US | claimed |
| US-4329439-A | AN ORGANOLITHIUM COMPONENT, AND AN AMINO-ACETAL COMPONENT OF THE CATALYST | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| US-4280927-A | A CHELATE OF HYDROCARBYL LITHIUM AND A DIALKYLAMINOALDEHYDE DIALKYL ACETAL | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| CN-120831429-A | Method for measuring chloroacetaldehyde in dimethylaminoacetaldehyde diethyl acetal by pre-column derivatization HPLC-UV method | 江苏晶立信医药科技有限公司 | 2025-10-24 | — | — | CN | disclosed |
| CN-120831429-A | Method for measuring chloroacetaldehyde in dimethylaminoacetaldehyde diethyl acetal by pre-column derivatization HPLC-UV method | 江苏晶立信医药科技有限公司 | 2025-10-24 | — | — | CN | disclosed |
| US-4066671-A | (2,2-Diethoxyethyl)dimethyl[5-(4-nitrophenyl)-2-furoylmethyl]ammonium chloride hemihydrate | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4038386-A | INOTROPIC AGENTS | DEUTSCH GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4028359-A | 2-Diethoxyethyl(dimethyl)(2-(2,4-diphenyl-5-pyrimidyl)-2-oxoethyl)ammonium bromide | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107172-A1 | PROCESS FOR THE PREPARATION OF 4-DIMETHYLAMINOCROTONIC ACID | EGFR, MET, ABL1 | THRB 1534/4885LMNA 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.