Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686817 | 0.96 | PDE2A (0.46) | MALT1PDE2AHDAC3HDAC1HDAC2 | |
| SCHEMBL22684760 | 0.92 | WDR91 (0.53) | MALT1PDE2ASTAT3STAT1PTGS1 | |
| SCHEMBL22685206 | 0.90 | PDE2A (0.48) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685246 | 0.88 | WDR91 (0.45) | MALT1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685182 | 0.88 | PDE2A (0.41) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22686821 | 0.88 | MALT1 (0.45) | MALT1PDE2AHDAC3HDAC1HDAC2 | |
| SCHEMBL22685207 | 0.88 | PDE2A (0.43) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685260 | 0.87 | MALT1 (0.45) | MALT1PDE2AHDAC3HDAC1HDAC2 | |
| SCHEMBL22686813 | 0.86 | PDE2A (0.42) | MALT1PDE2AHDAC3HDAC1HDAC2 | |
| SCHEMBL22686807 | 0.86 | PDE2A (0.43) | MALT1PDE2AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047877-A | Novel amide compound and use thereof | 和记黄埔医药（上海）有限公司 | 2020-12-08 | — | — | CN | disclosed |
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |