Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 10/20 | 0.53 |
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22684763 | 0.92 | PDE2A (0.44) | WDR91PDE2APTGS1TRPV1BACE1 | |
| SCHEMBL22657408 | 0.92 | MALT1 (0.45) | WDR91PDE2AMALT1STAT3STAT1 | |
| SCHEMBL22686817 | 0.90 | PDE2A (0.46) | WDR91PDE2AMALT1STAT3STAT1 | |
| SCHEMBL22684762 | 0.88 | PDE2A (0.42) | WDR91PDE2APTGS1TRPV1BACE1 | |
| SCHEMBL22685206 | 0.82 | PDE2A (0.48) | PDE2APTGS1 | |
| SCHEMBL22685078 | 0.81 | WDR91 (0.53) | WDR91PDE2AMALT1 | |
| SCHEMBL22686821 | 0.80 | MALT1 (0.45) | WDR91PDE2AMALT1STAT3STAT1 | |
| SCHEMBL22685182 | 0.80 | PDE2A (0.41) | PDE2APTGS1TRPV1 | |
| SCHEMBL22685207 | 0.80 | PDE2A (0.43) | PDE2A | |
| SCHEMBL22685246 | 0.79 | WDR91 (0.45) | WDR91MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |