Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685263 | 0.90 | HDAC3 (0.44) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22657408 | 0.88 | MALT1 (0.45) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685183 | 0.88 | MALT1 (0.44) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685339 | 0.88 | WDR91 (0.41) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685203 | 0.87 | PDE2A (0.47) | HDAC3HDAC1HDAC2HDAC6AKT1 | |
| SCHEMBL22685181 | 0.87 | IDO1 (0.41) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685345 | 0.85 | PDE2A (0.44) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22686817 | 0.84 | PDE2A (0.46) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684761 | 0.82 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC6MAPK1 | |
| SCHEMBL22686808 | 0.82 | PDE2A (0.46) | WDR91AKT1F10MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |