Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 12/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685206 | 0.90 | PDE2A (0.48) | PDE2APTGER4PTGER2HDAC3HDAC1 | |
| SCHEMBL22657408 | 0.88 | MALT1 (0.45) | PDE2APTGER4HDAC3HDAC1HDAC2 | |
| SCHEMBL22685182 | 0.85 | PDE2A (0.41) | PDE2APTGER4PTGER2HDAC3HDAC1 | |
| SCHEMBL22686817 | 0.84 | PDE2A (0.46) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684763 | 0.80 | PDE2A (0.44) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684760 | 0.80 | WDR91 (0.53) | PDE2A | |
| SCHEMBL22686802 | 0.79 | AKT1 (0.41) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22686821 | 0.78 | MALT1 (0.45) | PDE2APTGER4HDAC3HDAC1HDAC2 | |
| SCHEMBL22684761 | 0.77 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684764 | 0.77 | HDAC1 (0.42) | PDE2AHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |