Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812697 | 0.83 | PTGDR2 (0.67) | PTGDR2PTGS2RAB9APOLBPTPRC | |
| SCHEMBL29408235 | 0.80 | PTGDR2 (0.63) | PTGDR2PTGS2RAB9APOLBMEN1 | |
| SCHEMBL10933113 | 0.80 | PTGDR2 (0.63) | PTGDR2PTGS2RAB9APOLBMEN1 | |
| SCHEMBL28686843 | 0.80 | MAPT (0.45) | PTGDR2RAB9APTPRCBCHEACHE | |
| SCHEMBL8609293 | 0.79 | MAPT (0.51) | RAB9APOLBMEN1KMT2AMAPT | |
| SCHEMBL28845383 | 0.78 | PTGDR2 (0.68) | PTGDR2PTGS2RAB9APOLBPTPRC | |
| SCHEMBL9526847 | 0.76 | HSPB1 (0.51) | RAB9APOLBMEN1KMT2AMAPT | |
| SCHEMBL7269589 | 0.76 | FNTA (0.50) | RAB9APOLBMEN1KMT2AMAPT | |
| SCHEMBL7269583 | 0.76 | FNTA (0.50) | RAB9APOLBMEN1KMT2AMAPT | |
| SCHEMBL28207049 | 0.76 | PTGS2 (0.73) | PTGDR2PTGS2RAB9APOLBPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969439-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-03-23 | — | — | EP | disclosed |
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |
| WO-2020230134-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |