Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.48 |
| ▸ | THRA | P10827 | 13/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660331 | 0.91 | THRB (0.45) | THRBTHRARORC | |
| SCHEMBL22660361 | 0.85 | THRB (0.46) | THRBTHRARORC | |
| SCHEMBL22660360 | 0.84 | THRB (0.44) | THRBTHRARORC | |
| SCHEMBL22668180 | 0.83 | THRB (0.71) | THRBTHRA | |
| SCHEMBL2921895 | 0.82 | THRA (0.67) | THRBTHRA | |
| SCHEMBL22668330 | 0.81 | THRB (0.51) | THRBTHRARORC | |
| SCHEMBL2925463 | 0.79 | THRB (0.54) | THRBTHRARORC | |
| SCHEMBL28500041 | 0.79 | THRB (0.49) | THRBTHRARORC | |
| SCHEMBL28564400 | 0.78 | THRB (0.48) | THRBTHRARORC | |
| SCHEMBL28489632 | 0.77 | THRB (0.45) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228577-A1 | PYRIDAZINONE DERIVATIVE AND USE THEREOF | 深圳微芯生物科技股份有限公司 | 2020-11-19 | — | — | WO | disclosed |