Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.49 |
| ▸ | THRA | P10827 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399816 | 0.90 | LMNA (0.47) | THRBTHRAALDH1A1HTTKDM4E | |
| SCHEMBL22660344 | 0.90 | LMNA (0.47) | THRBTHRAALDH1A1HTTKDM4E | |
| SCHEMBL2921895 | 0.84 | THRA (0.67) | THRBTHRA | |
| SCHEMBL22660382 | 0.84 | THRB (0.44) | THRBTHRA | |
| SCHEMBL22668330 | 0.82 | THRB (0.51) | THRBTHRARORC | |
| SCHEMBL22660347 | 0.82 | THRB (0.74) | THRBTHRA | |
| SCHEMBL22660397 | 0.81 | THRB (0.42) | THRBTHRA | |
| SCHEMBL2925463 | 0.81 | THRB (0.54) | THRBTHRARORC | |
| SCHEMBL28564400 | 0.79 | THRB (0.48) | THRBTHRARORC | |
| SCHEMBL22660400 | 0.79 | THRB (0.48) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909137-B | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-111909137-A | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2020-11-10 | — | — | CN | disclosed |