SCHEMBL22661237

SCHEMBL22661237

Cc1c(C(=O)Cl)c(I)c(N)c(I)c1C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25779596 0.87
SCHEMBL24251717 0.86 POLB (0.33)
SCHEMBL11195794 0.83 ALDH1A1 (0.32)
SCHEMBL620188 0.83 ALDH1A1 (0.32)
SCHEMBL28659602 0.79 ALDH1A1 (0.34)
SCHEMBL22661221 0.79 KDM4E (0.38)
SCHEMBL14156178 0.78 ALDH1A1 (0.32)
SCHEMBL28771911 0.76 ALDH1A1 (0.31)
SCHEMBL3660895 0.76
SCHEMBL12957727 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210284597-A1 Process for the Monotopic Preparation of Intermediate Organo-Iodinated Compounds for the Synthesis of Ioversol GUERBET (FR) 2021-09-16 US disclosed
US-10836711-B2 Method for the one-pot production of organo-iodinated compounds GUERBET (FR) 2020-11-17 US disclosed