⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787529 | 0.91 | POLB (0.33) | — | |
| SCHEMBL620188 | 0.91 | ALDH1A1 (0.32) | — | |
| SCHEMBL4833943 | 0.89 | POLB (0.35) | — | |
| SCHEMBL11195794 | 0.86 | ALDH1A1 (0.32) | — | |
| SCHEMBL6563535 | 0.86 | POLB (0.33) | — | |
| SCHEMBL9563941 | 0.84 | POLB (0.35) | — | |
| Malonic Acid SCHEMBL11132579 | 0.83 | LDHA (0.36) | — | |
| SCHEMBL12957727 | 0.83 | — | — | |
| Adipic Acid SCHEMBL11497568 | 0.80 | LMNA (0.41) | — | |
| SCHEMBL3664084 | 0.80 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680334-B2 | Process for the preparation of iosimenol | MALLINCKRODT LLC (US) | 2014-03-25 | — | — | US | claimed |
| US-20130261338-A1 | Process for the Preparation of Iosimenol | MALLINCKRODT LLC (US) | 2013-10-03 | — | — | US | claimed |
| US-8445725-B2 | Process for the preparation of iosimenol | MALLINCKRODT LLC (US) | 2013-05-21 | — | — | US | claimed |
| EP-2240432-B1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT LLC (US) | 2012-07-04 | — | — | EP | claimed |
| US-20100280270-A1 | Process for the Prepartion of Iosimenol | MNK 2011 LLC (F/K/A MALLINCKRODT INC.) | 2010-11-04 | — | — | US | claimed |
| EP-2240432-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | Mallinckrodt Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009091758-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT INC. (US) | 2009-07-23 | — | — | WO | claimed |
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMA CO LTD (JP) | 2022-02-17 | — | — | US | disclosed |
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMA CO LTD (JP) | 2022-02-17 | — | — | US | disclosed |
| US-20200095191-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-26 | — | — | US | disclosed |
| EP-3619192-A1 | PROCESS OF PREPARING IOSIMENOL | Otsuka Pharmaceutical Co., Ltd. (JP) | 2020-03-11 | — | — | EP | disclosed |
| CN-110573493-A | Method for preparing iomesol | 大塚制药株式会社 | 2019-12-13 | — | — | CN | disclosed |
| WO-2018203525-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-08 | — | — | WO | disclosed |
| EP-2240432-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | Mallinckrodt Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-2240432-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | Mallinckrodt Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009091758-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| WO-2009091758-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| US-5698739-A | RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |