Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25779596 | 0.86 | — | — | |
| SCHEMBL22661237 | 0.86 | — | — | |
| SCHEMBL24251777 | 0.83 | POLB (0.34) | POLB | |
| SCHEMBL3660895 | 0.76 | — | — | |
| SCHEMBL14156178 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL24251718 | 0.73 | KMT2A (0.38) | POLB | |
| SCHEMBL22661223 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL16781055 | 0.72 | POLB (0.55) | POLB | |
| SCHEMBL11195794 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL620188 | 0.71 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMA CO LTD (JP) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | AOC2, SSTR2, NISCH | POLB 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.