Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15481075 | 0.85 | LMNA (0.46) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL22667102 | 0.85 | APAF1 (0.32) | LMNAAPAF1POLBALDH1A1GAA | |
| SCHEMBL22667101 | 0.80 | HDAC3 (0.32) | — | |
| SCHEMBL2737300 | 0.79 | GAA (0.46) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL20320332 | 0.79 | LMNA (0.56) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL24666100 | 0.78 | LMNA (0.44) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL17324186 | 0.78 | LMNA (0.40) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL17321052 | 0.76 | KCNJ6 (0.39) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL21960349 | 0.76 | POLB (0.49) | LMNAAPAF1POLBKDM4EALDH1A1 | |
| SCHEMBL2737348 | 0.76 | ADORA2B (0.42) | LMNAAPAF1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228687-A1 | 4-AMINOFURAN-2 (5H) ONE DERIVATIVES, PREPARATION METHODS AND APPLICATIONS THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2020-11-19 | — | — | WO | disclosed |