Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CPA1 | P15085 | 7/20 | 0.56 |
| ▸ | CPA3 | P15088 | 3/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719401 | 0.89 | CPA1 (0.72) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL8040411 | 0.88 | CYP1A2 (0.68) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL6717333 | 0.84 | CYP1A2 (0.63) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL27788634 | 0.82 | CYP1A2 (0.52) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL28901708 | 0.82 | CPA3 (0.54) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL8813761 | 0.81 | CPA3 (0.59) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL7752235 | 0.81 | KMT2A (0.53) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL3555234 | 0.81 | CYP1A2 (0.64) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL1539262 | 0.79 | FOLH1 (0.53) | CYP1A2CPA1CPA3CPB1CPB2 | |
| SCHEMBL24236690 | 0.78 | CYP1A2 (0.55) | CYP1A2CPA1CPA3CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371070-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-12-18 | — | — | US | disclosed |
| EP-2791114-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| CN-104011023-A | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG | 2014-08-27 | — | — | CN | disclosed |
| EP-2651917-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130266590-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2013-10-10 | — | — | US | disclosed |
| WO-2013087800-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-20 | — | — | WO | disclosed |
| US-8445440-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2013-05-21 | — | — | US | disclosed |
| EP-2539333-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012080260-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011104266-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-08-25 | — | — | US | disclosed |
| WO-1997013750-A1 | AZETIDINONES AND THEIR THERAPEUTIC USE AS CYTOKINE INHIBITORS | CHIROSCIENCE LIMITED (GB) | 1997-04-17 | — | — | WO | disclosed |
| EP-0302516-B1 | Optical article made of amorphous thermoplastic polyester resin | MITSUBISHI RAYON CO (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0513703-A2 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle | MAGIS FARMACEUTICI S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |
| US-4910291-A | From aromatic diacid | MITSUBISHI RAYON COMPANY LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0302516-A2 | Optical article made of amorphous thermoplastic polyester resin | MITSUBISHI RAYON CO., LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130266590-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | CYP1A2 4861/4885CPA1 1301/4885CPA3 2594/4885 |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | CYP1A2 4828/4885CPA1 963/4885CPA3 2557/4885 |
| US-20140371070-A1 | PLANT GROWTH REGULATING COMPOUNDS | SREBF1, SREBF2, OSBP | CYP1A2 3582/4885CPA1 2967/4885CPA3 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.