SCHEMBL7752235

SCHEMBL7752235

COC(=O)[C@H](CC(=O)Cl)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 1/20 0.50
CPA1 P15085 2/20 0.49
CPB1 P15086 1/20 0.49
CPA3 P15088 1/20 0.49
CPB2 Q96IY4 1/20 0.49
BIRC2 Q13490 1/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 1/20 0.47
THRB P10828 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
LTA4H P09960 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901408 0.87 CPA1 (0.66) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL1914987 0.87 CPA1 (0.66) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL2398335 0.87 CPA1 (0.66) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL9755831 0.85 KMT2A (0.54) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL7506768 0.85 KMT2A (0.54) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL8999162 0.84 KMT2A (0.53) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL3596338 0.81 ALDH1A1 (0.57) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL117431 0.81 CYP1A2 (0.60) KMT2ACYP1A2CPA1CPB1CPA3
SCHEMBL1719401 0.81 CPA1 (0.72) CYP1A2CPA1CPB1CPA3CPB2
SCHEMBL2266746 0.81 CYP1A2 (0.59) CYP1A2CPA1CPB1CPA3CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001261645-A (3S)-3-METHOXYCARBONYL-4-PHENYLBUTYRYL CHLORIDE AND METHOD FOR USING THE SAME KISSEI PHARMACEUT CO LTD 2001-09-26 JP disclosed