SCHEMBL1719401

SCHEMBL1719401

O=C(Cl)CC(Cc1ccccc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 10/20 0.72
CPA3 P15088 3/20 0.72
CPB1 P15086 1/20 0.72
CPB2 Q96IY4 1/20 0.72
CYP1A2 P05177 1/20 0.70
MME P08473 1/20 0.62
FOLH1 Q04609 1/20 0.61
KMO O15229 1/20 0.56
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2266746 0.89 CYP1A2 (0.59) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL5688996 0.84 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL1915564 0.84 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL393002 0.84 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL4664822 0.83 CYP1A2 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL3421012 0.82 CPA1 (0.96) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL7286643 0.81 CPA1 (0.70) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL7439697 0.81 CYP1A2 (0.86) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL9622038 0.81 CYP1A2 (0.86) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL22115491 0.81 CYP1A2 (0.95) CPA1CPA3CPB1CPB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167024-B1 COOLING COMPOUNDS GIVAUDAN SA (CH) 2012-01-11 EP disclosed
US-7959958-B2 Cooling compounds Givaudan, S.A. (CH) 2011-06-14 US disclosed
EP-2167024-A2 COOLING COMPOUNDS Givaudan SA (CH) 2010-03-31 EP disclosed
US-20080311232-A1 Cooling Compounds GIVAUDAN, SA (CH) 2008-12-18 US disclosed
WO-2008151460-A2 COOLING COMPOUNDS GIVAUDAN SA (CH) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311232-A1 Cooling Compounds MAL2, NCOR2, NCOA2 CPA1 3888/4885CPA3 2981/4885CPB1 2905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.