Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 10/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 10/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27820991 | 0.86 | MEN1 (0.48) | ADRB1 | |
| SCHEMBL27844755 | 0.85 | ALDH1A1 (0.48) | ADRB1 | |
| SCHEMBL27862517 | 0.83 | ADRB1 (0.46) | ADRB1HTR3A | |
| SCHEMBL5231120 | 0.82 | ADRB1 (0.86) | ADRB1CHRNB2CHRNA4HTR7HTR3A | |
| SCHEMBL21533600 | 0.79 | ADRB1 (0.65) | ADRB1CHRNB2CHRNA4HTR7HTR3A | |
| SCHEMBL5238705 | 0.78 | ADRB1 (0.63) | ADRB1CHRNB2CHRNA4HTR7HTR3A | |
| SCHEMBL22818466 | 0.75 | ADRB1 (0.59) | ADRB1CHRNB2CHRNA4HTR7HTR3A | |
| SCHEMBL5206787 | 0.75 | ADRB1 (0.63) | ADRB1CHRNB2CHRNA4HTR7HTR3A | |
| SCHEMBL5235956 | 0.75 | ADRB1 (0.63) | ADRB1CHRNB2CHRNA4HTR7HTR3A | |
| SCHEMBL221254 | 0.74 | ADRB1 (1.00) | ADRB1HTR7HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020231806-A1 | PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2020-11-19 | — | — | WO | disclosed |