Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.56 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 12/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31145840 | 0.86 | CD274 (0.58) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL22675483 | 0.75 | PARP1 (0.40) | CD274PDCD1LG2PDCD1PARP1 | |
| SCHEMBL23198417 | 0.74 | CD274 (0.54) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL25720163 | 0.73 | MAPK1 (0.50) | CD274PDCD1PARP1 | |
| SCHEMBL21507062 | 0.72 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL1776816 | 0.72 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27717312 | 0.72 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24722594 | 0.72 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL20312849 | 0.72 | CD274 (0.57) | CD274PDCD1PARP1 | |
| SCHEMBL24345978 | 0.71 | CD274 (0.53) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228649-A1 | SUBSTITUTED PHENYLPROPENYLPYRIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |