Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.46 |
| ▸ | FEN1 | P39748 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 5/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26585989 | 0.85 | ALOX5AP (0.50) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL25714089 | 0.85 | ALOX5AP (0.45) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL24773521 | 0.85 | ALOX5AP (0.45) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL30306048 | 0.85 | ALOX5AP (0.45) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL22677156 | 0.82 | ALOX5AP (0.43) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL31129024 | 0.79 | RXRA (0.45) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL22659251 | 0.76 | ALOX5AP (0.39) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL25129367 | 0.76 | ALOX5AP (0.41) | ALOX5APFEN1TRPA1CYP3A4CYP2D6 | |
| SCHEMBL8049520 | 0.76 | UHRF1 (0.46) | HTR1ASLC6A2SLC6A4TRPA1UHRF1 | |
| SCHEMBL16502358 | 0.76 | GRM2 (0.43) | HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2022109577-A1 | FGFR INHIBITORS AND METHODS OF MAKING AND USING THE SAME | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2020231990-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2020-11-19 | — | — | WO | disclosed |