SCHEMBL2267686

SCHEMBL2267686

CN(C)C=C([SiH3])c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.44
ALDH1A1 P00352 4/20 0.41
MAPT P10636 1/20 0.41
HSP90AA1 P07900 1/20 0.40
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.37
RAB9A P51151 3/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
HIF1A Q16665 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2277485 0.77 ALDH1A1 (0.38) ALDH1A1MAPTRAB9AKMT2AMEN1
SCHEMBL22484566 0.76 RECQL (0.47) RECQLALDH1A1MAPTHSP90AA1KDM4E
SCHEMBL28081835 0.76 RECQL (0.47) RECQLALDH1A1MAPTHSP90AA1KDM4E
SCHEMBL8401904 0.75 CES2 (0.39) RECQLALDH1A1MAPTHSP90AA1POLB
SCHEMBL8576134 0.74 RECQL (0.45) RECQLALDH1A1MAPTHSP90AA1KDM4E
SCHEMBL8859071 0.73 RECQL (0.44) RECQLALDH1A1MAPTHSP90AA1KDM4E
SCHEMBL25274689 0.70 AKR1C1 (0.53) RECQLALDH1A1KDM4ELMNARAB9A
SCHEMBL1796055 0.70 POLB (0.64) RECQLALDH1A1MAPTHSP90AA1KDM4E
SCHEMBL3559979 0.70 CES2 (0.52) RECQLALDH1A1MAPTKDM4ELMNA
SCHEMBL18884804 0.70 AKT1 (0.43) RECQLALDH1A1MAPTHSP90AA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed