SCHEMBL2277485

SCHEMBL2277485

CCN(C=C([SiH3])c1ccccc1)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
HPGD P15428 2/20 0.38
PGR P06401 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
HTR2A P28223 1/20 0.38
HRH1 P35367 1/20 0.38
KCNH2 Q12809 1/20 0.38
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 1/20 0.38
ATM Q13315 1/20 0.36
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
ESRRG P62508 1/20 0.35
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
MAPT P10636 2/20 0.34
HDAC1 Q13547 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422795 0.79 ALDH1A1 (0.40) ALDH1A1HPGDPGRADRA2AADRA2B
SCHEMBL19803812 0.78 ALDH1A1 (0.39) ALDH1A1HPGDPGRADRA2AADRA2B
SCHEMBL136255 0.78 ALDH1A1 (0.39) ALDH1A1HPGDPGRADRA2AADRA2B
SCHEMBL2267686 0.77 RECQL (0.44) ALDH1A1HPGDKMT2AMEN1MAPT
SCHEMBL28110277 0.72 ATM (0.40) ALDH1A1HPGDKMT2ASMN1; SMN2NPSR1
SCHEMBL11754203 0.72 ALDH1A1 (0.47) ALDH1A1HPGDKMT2ASMN1; SMN2MEN1
SCHEMBL19040950 0.72 ALDH1A1 (0.44) ALDH1A1HPGDPGRADRA2AADRA2B
SCHEMBL19041280 0.72 CES2 (0.53) ALDH1A1HPGDPGRADRA2AADRA2B
SCHEMBL11278094 0.72 ALDH1A1 (0.44) ALDH1A1HPGDPGRADRA2AADRA2B
SCHEMBL11278110 0.72 ALDH1A1 (0.44) ALDH1A1HPGDPGRADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed