Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM5C | P41229 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311687 | 0.81 | KDM4C (0.56) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL31085057 | 0.81 | KDM4C (0.56) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL29541336 | 0.81 | KDM4C (0.71) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL648273 | 0.81 | KDM4C (0.71) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL22013781 | 0.81 | KAT6A (0.49) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL13702118 | 0.80 | KAT6A (0.56) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL3737328 | 0.80 | KDM4C (0.69) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL946431 | 0.78 | ASIC3 (0.55) | KAT6AKDM4CKDM4EKDM4AKDM6B | |
| SCHEMBL10276830 | 0.78 | KMO (0.60) | KDM4EKMODBHGAARECQL | |
| SCHEMBL14241145 | 0.77 | MAPT (0.54) | KAT6AKDM4CKDM4EKDM4AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279733-B2 | Peptide antibiotics | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-03-22 | — | — | US | disclosed |
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NGLY1, VIP, PEPD | KAT6A 3541/4885KDM4C 4814/4885KDM4E 4639/4885 |
| US-11279733-B2 | Peptide antibiotics | NGLY1, VIP, PEPD | KAT6A 3541/4885KDM4C 4814/4885KDM4E 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.