Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904011 | 0.82 | HTR2C (0.66) | HTR2CSIGMAR1 | |
| SCHEMBL3686869 | 0.78 | HTR2C (0.44) | HTR2CSIGMAR1IDO1IKBKBCHRNB4 | |
| SCHEMBL10354111 | 0.78 | HSD17B1 (0.47) | HTR2CSIGMAR1ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11019773 | 0.76 | PIK3CD (0.46) | HTR2CSIGMAR1ALDH1A1HSD17B10 | |
| SCHEMBL9249946 | 0.76 | HTR2C (0.68) | HTR2CSIGMAR1ALDH1A1 | |
| SCHEMBL2173351 | 0.76 | SIGMAR1 (0.65) | HTR2CSIGMAR1ALDH1A1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL10354116 | 0.74 | HTR2C (0.67) | HTR2CSIGMAR1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10354136 | 0.74 | HTR2C (0.72) | HTR2CHRH1HRH4SIGMAR1IDO1 | |
| SCHEMBL10353908 | 0.74 | NCOA1 (0.46) | HTR2CGAAMAPTKDM4ENCOA1 | |
| SCHEMBL4789903 | 0.73 | ADRA2A (0.41) | HTR2CHRH1HRH4IDO1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306529-A2 | FGFR INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2020231990-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2020-11-19 | — | — | WO | disclosed |