SCHEMBL2267937

SCHEMBL2267937

CN(C)[SiH](C)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TSHR P16473 3/20 0.35
KCNN4 O15554 1/20 0.35
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2A P28223 2/20 0.32
HRH1 P35367 2/20 0.32
AOC3 Q16853 2/20 0.32
TAAR1 Q96RJ0 2/20 0.32
MAPT P10636 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
HIF1A Q16665 1/20 0.31
TDP1 Q9NUW8 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153983 1.00 ALDH1A1 (0.35) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL29958568 0.85 ALDH1A1 (0.30) ALDH1A1TSHRHSD17B10
SCHEMBL2271915 0.74 ALDH1A1 (0.36) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL22719556 0.74 TAAR1 (0.31) ALDH1A1TSHRKCNN4TAAR1
SCHEMBL2099548 0.74 ALDH1A1 (0.36) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL9621566 0.74 MEN1 (0.36) ALDH1A1TSHRMEN1HTTKMT2A
SCHEMBL2268251 0.72 L3MBTL1 (0.35) ALDH1A1TSHRHTTAOC3MAPT
SCHEMBL766067 0.71 ESR1 (0.32)
SCHEMBL2100320 0.70 HTR2A (0.36) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL1539360 0.69 TSHR (0.39) ALDH1A1TSHRLMNAALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540084-B1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM SPA (IT) 1996-09-04 EP claimed
EP-0540084-A1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM S.p.A. (IT) 1993-05-05 EP claimed
US-5208069-A Silane precursor ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1993-05-04 US claimed
CN-107236061-A Amino silane initiator and functionalized polymeric prepared therefrom 株式会社普利司通 2017-10-10 CN disclosed
CN-103313863-B Aminosilane initiators and functionalized polymers prepared therefrom 株式会社普利司通 2017-06-20 CN disclosed
CN-103313863-A Aminosilane initiators and functionalized polymers prepared therefrom BRIDGESTONE CORP 2013-09-18 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
EP-0540084-B1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM SPA (IT) 1996-09-04 EP disclosed
EP-0540084-A1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM S.p.A. (IT) 1993-05-05 EP disclosed
US-5208069-A Silane precursor ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1993-05-04 US disclosed