SCHEMBL2099548

SCHEMBL2099548

CN(C)[SiH](c1ccccc1)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TSHR P16473 4/20 0.36
KCNN4 O15554 1/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 2/20 0.33
HTR2A P28223 2/20 0.33
HRH1 P35367 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
MAPT P10636 1/20 0.33
AOC3 Q16853 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2104061 0.81 TSHR (0.33) ALDH1A1TSHRHTTLMNAHTR2A
SCHEMBL2271915 0.77 ALDH1A1 (0.36) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL2153983 0.74 ALDH1A1 (0.35) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL2267937 0.74 ALDH1A1 (0.35) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL2100320 0.72 HTR2A (0.36) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL2100542 0.70 L3MBTL1 (0.36) ALDH1A1TSHRHTTLMNAAOC3
SCHEMBL2271802 0.69 TSHR (0.41) ALDH1A1TSHRHTR2AHRH1TAAR1
SCHEMBL2273295 0.69 KCNN4 (0.36) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL2273356 0.69 ALDH1A1 (0.34) ALDH1A1TSHRKCNN4MEN1HTT
SCHEMBL2267681 0.67 ALDH1A1 (0.33) ALDH1A1TSHRKCNN4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671483-B1 Method for vapor deposition of a ceramic coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM SPA (IT) 1997-12-29 EP claimed
EP-0540084-B1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM SPA (IT) 1996-09-04 EP claimed
EP-0671483-A1 Ceramic vapor deposited coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM S.p.A. (IT) 1995-09-13 EP claimed
US-5424095-A Decomposing organosilicon precursor inside chemical reactor to form film of ceramic material on surface; prevents coking ENIRICERCHE S.P.A. (IT) 1995-06-13 US claimed
EP-0540084-A1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM S.p.A. (IT) 1993-05-05 EP claimed
US-5208069-A Silane precursor ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1993-05-04 US claimed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed
EP-0671483-B1 Method for vapor deposition of a ceramic coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM SPA (IT) 1997-12-29 EP disclosed
EP-0540084-B1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM SPA (IT) 1996-09-04 EP disclosed
EP-0671483-A1 Ceramic vapor deposited coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM S.p.A. (IT) 1995-09-13 EP disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4400526-A Hydrogen bearing silyl carbamates UNION CARBIDE CORPORATION (US) 1983-08-23 US disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4208492-A ENGINEERING THERMOPLASTIC ELASTOMERS UNION CARBIDE CORPORATION (US) 1980-06-17 US disclosed
US-4145504-A High temperature carborane-siloxane elastomers intermediate polymeric products and process for preparation UNION CARBIDE CORPORATION (US) 1979-03-20 US disclosed