SCHEMBL22679491

SCHEMBL22679491

Cc1cc(C)c(-c2ccc3c(c2)c2cccc4c5cc(-c6cc7c8ccccc8n8c9ccc(-c%10ccccc%10)cc9c(c6)c78)ccc5n3c42)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.39
ALKBH5 Q6P6C2 1/20 0.37
FTO Q9C0B1 1/20 0.37
PSMB5 P28074 1/20 0.36
NPY5R Q15761 2/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
DNM1 Q05193 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
NR4A2 P43354 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
TNKS2 Q9H2K2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460073 0.92 ALKBH5 (0.41) TSPOALKBH5FTONPY5RDNM1
SCHEMBL21710652 0.92 ALKBH5 (0.42) TSPOALKBH5FTOPSMB5NPY5R
SCHEMBL15460134 0.91 ALKBH5 (0.40) TSPOALKBH5FTONPY5RCYP1A2
SCHEMBL16621648 0.88 TSPO (0.43) TSPOALKBH5FTOPSMB5NPY5R
SCHEMBL15460137 0.88 TSPO (0.43) TSPOALKBH5FTOPSMB5NPY5R
SCHEMBL15460140 0.88 TSPO (0.43) TSPOALKBH5FTOPSMB5NPY5R
SCHEMBL16621637 0.88 TSPO (0.45) TSPOPSMB5NPY5RDNM1KDM4E
SCHEMBL23823892 0.88 TSPO (0.44) TSPOALKBH5FTONPY5RDNM1
SCHEMBL16621723 0.88 TSPO (0.44) TSPOALKBH5FTONPY5RDNM1
SCHEMBL16621741 0.88 TSPO (0.44) TSPOALKBH5FTONPY5RDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-20200365812-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-11-19 US disclosed