SCHEMBL21710652

SCHEMBL21710652

Cc1cc(C)c(-c2ccc3c(c2)c2cccc4c5ccccc5n3c42)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.42
FTO Q9C0B1 1/20 0.42
CYP1A2 P05177 2/20 0.40
CYP2A6 P11509 1/20 0.40
MAPT P10636 6/20 0.36
KDM4E B2RXH2 6/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HTT P42858 3/20 0.36
POLB P06746 1/20 0.36
NPY5R Q15761 2/20 0.36
HSD17B10 Q99714 2/20 0.33
TSPO P30536 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CHEK1 O14757 1/20 0.33
MAPK1 P28482 1/20 0.33
HBB P68871 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22679491 0.92 TSPO (0.39) ALKBH5FTOCYP1A2CYP2A6MAPT
SCHEMBL21710580 0.89 CYP1A2 (0.43) ALKBH5FTOCYP1A2CYP2A6MAPT
SCHEMBL21717857 0.89 CYP2A6 (0.42) ALKBH5FTOCYP1A2CYP2A6MAPT
SCHEMBL15460073 0.88 ALKBH5 (0.41) ALKBH5FTOMAPTKDM4EMEN1
SCHEMBL15460134 0.87 ALKBH5 (0.40) ALKBH5FTOCYP1A2MAPTKDM4E
SCHEMBL15460062 0.87 ALKBH5 (0.45) ALKBH5FTOCYP1A2MAPTKDM4E
SCHEMBL21717353 0.86 ALKBH5 (0.40) ALKBH5FTOCYP1A2CYP2A6MAPT
SCHEMBL22679479 0.85 CYP1A2 (0.40) ALKBH5FTOCYP1A2CYP2A6MAPT
SCHEMBL24601459 0.85 CYP1A2 (0.40) ALKBH5FTOCYP1A2CYP2A6MAPT
SCHEMBL21710649 0.85 PTGER4 (0.39) ALKBH5FTOMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-20210005825-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2021-01-07 US disclosed
US-20210005826-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2021-01-07 US disclosed
US-20200052212-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ESR2 ALKBH5 2390/4885FTO 464/4885CYP1A2 1303/4885
US-20210005825-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE OR51E2, CD99, CTNND1 ALKBH5 1574/4885FTO 40/4885CYP1A2 259/4885
US-20210005826-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC APPARATUS EML4, EBPL, LEF1 ALKBH5 899/4885FTO 16/4885CYP1A2 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.