Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | ODC1 | P11926 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237667 | 1.00 | ABCB1 (0.71) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL16894617 | 0.88 | ABCB1 (0.74) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL1765114 | 0.83 | ABCB1 (1.00) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL17258306 | 0.81 | ABCB1 (0.61) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL16894663 | 0.81 | ODC1 (0.68) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL7199710 | 0.80 | MEN1 (0.69) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| Baicalein Trimethyl Ether SCHEMBL971297 | 0.79 | ABCB1 (0.80) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL7773355 | 0.79 | QPCT (0.53) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| Sinensetin SCHEMBL29700880 | 0.78 | ABCB1 (1.00) | ABCB1MEN1KMT2AALDH1A1ABCG2 | |
| Tetramethylscutellarein SCHEMBL739115 | 0.78 | MEN1 (1.00) | ABCB1MEN1KMT2AALDH1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230041523-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-02-09 | — | — | US | disclosed |
| WO-2020232255-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230041523-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS | NLN, GLS, PRNP | ABCB1 3765/4885MEN1 3772/4885KMT2A 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.