Baicalein Trimethyl Ether

Baicalein Trimethyl Ether

SCHEMBL971297

COc1cc2oc(-c3ccccc3)cc(=O)c2c(OC)c1OC

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 5/20 0.80
ABCG2 Q9UNQ0 4/20 0.80
ALDH1A1 P00352 4/20 0.78
MEN1 O00255 3/20 0.78
KMT2A Q03164 3/20 0.78
TP53 P04637 3/20 0.73
MDM2 Q00987 1/20 0.73
KDM4E B2RXH2 4/20 0.71
NPC1 O15118 1/20 0.71
RAB9A P51151 1/20 0.71
CYP3A4 P08684 3/20 0.70
MAPT P10636 3/20 0.70
HPGD P15428 2/20 0.70
HSD17B10 Q99714 2/20 0.70
AR P10275 1/20 0.70
CYP1A1 P04798 1/20 0.68
CYP1B1 Q16678 1/20 0.68
FLT3 P36888 2/20 0.66
SLCO2B1 O94956 1/20 0.66
PRSS1 P07477 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mosloflavone SCHEMBL971985 0.89 KDM4E (0.81) ABCB1ABCG2ALDH1A1MEN1KMT2A
Mosloflavone SCHEMBL29477310 0.89 KDM4E (0.81) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL974333 0.89 ABCB1 (0.68) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL28645437 0.89 ABCB1 (0.76) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL28660389 0.88 KDM4E (0.81) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL30606765 0.88 KDM4E (0.81) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL970267 0.88 ABCB1 (0.91) ABCB1ABCG2ALDH1A1MEN1KMT2A
Tetramethylscutellarein SCHEMBL739115 0.87 MEN1 (1.00) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL1765114 0.87 ABCB1 (1.00) ABCB1ABCG2ALDH1A1MEN1KMT2A
SCHEMBL30082751 0.87 MEN1 (0.74) ABCB1ABCG2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005538-A Application of flavonoid compounds in treating cerebral small vessel diseases 南通大学 2026-05-12 CN claimed
CN-120146874-A Method and device for tracing origin of radix tetrastigme 中国农业科学院农业质量标准与检测技术研究所 2025-06-13 CN claimed
CN-115315194-A Hydroxy-and methoxy-substituted flavones and their use 弗门尼舍有限公司 2022-11-08 CN claimed
CN-114272335-A Traditional Chinese medicine formula for regulating and controlling intestinal function of children 华子昂 2022-04-05 CN claimed
CN-110498739-A A method of synthesis 6- hydroxyl -2,3,4- trimethoxy-alpha-chloro acetophenone UNIV SOUTH CHINA 2019-11-26 CN claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
CN-122005538-A Application of flavonoid compounds in treating cerebral small vessel diseases 南通大学 2026-05-12 CN disclosed
CN-122005538-A Application of flavonoid compounds in treating cerebral small vessel diseases 南通大学 2026-05-12 CN disclosed
CN-120146874-A Method and device for tracing origin of radix tetrastigme 中国农业科学院农业质量标准与检测技术研究所 2025-06-13 CN disclosed
US-20240024710-A1 NOSE PLUG WITH ANTI-MICROBIAL ACTIVITY NOSEOPTION AB (SE) 2024-01-25 US disclosed
EP-4267258-A1 NOSE PLUG WITH ANTI-MICROBIAL ACTIVITY NoseOption AB (SE) 2023-11-01 EP disclosed
CN-116847910-A Nasal plug with antimicrobial activity 诺斯欧博森公司 2023-10-03 CN disclosed
CN-115894422-A PPAR gamma agonist and combination and application thereof 上海中医药大学 2023-04-04 CN disclosed
WO-2003057210-A1 COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-07-17 WO disclosed
US-20030125264-A1 Methods For Treating Wounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-03 US disclosed
US-6555523-B1 Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus CASCADE ESTATES LTD. (MU) 2003-04-29 US disclosed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP disclosed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO disclosed
EP-0973523-A1 ANTI-MICROBIAL PRODUCT Richards, Robert Michael Edward (GB) 2000-01-26 EP disclosed
WO-1998036750-A1 ANTI-MICROBIAL PRODUCT BTG INTERNATIONAL LIMITED (GB) 1998-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125264-A1 Methods For Treating Wounds FGF2, MMP1, FIBP ABCB1 2498/4885ABCG2 3752/4885ALDH1A1 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.