Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gradenin A SCHEMBL16894613 | 0.88 | KDM4E (0.92) | ABCB1MEN1KMT2AABCG2TP53 | |
| Sinensetin SCHEMBL29700880 | 0.88 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| Sinensetin SCHEMBL29549544 | 0.88 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL1975675 | 0.88 | ABCB1 (0.79) | ABCB1MEN1KMT2AABCG2TP53 | |
| Sinensetin SCHEMBL621101 | 0.88 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL31558902 | 0.88 | KDM4E (0.82) | ABCB1MEN1KMT2AABCG2TP53 | |
| Gradenin A SCHEMBL29893822 | 0.88 | KDM4E (0.92) | ABCB1MEN1KMT2AABCG2TP53 | |
| Baicalein Trimethyl Ether SCHEMBL971297 | 0.87 | ABCB1 (0.80) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL1422009 | 0.87 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL29465904 | 0.87 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119745951-A | Application of nine-dragon vine extract in preparation of medicines for treating acute lung injury | 杭州医学院 | 2025-04-04 | — | — | CN | claimed |
| US-20220054448-A1 | NOVEL POLYMETHOXYFLAVONE COMPOUNDS FOR SKELETAL MUSCLE MODULATION, METHODS AND USES THEREOF | NESTLE SA (CH) | 2022-02-24 | — | — | US | claimed |
| EP-3897617-A1 | NOVEL POLYMETHOXYFLAVONE COMPOUNDS FOR SKELETAL MUSCLE MODULATION, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2021-10-27 | — | — | EP | claimed |
| CN-113164441-A | Novel polymethoxyflavone compounds for skeletal muscle modulation, methods and uses thereof | 雀巢产品有限公司 | 2021-07-23 | — | — | CN | claimed |
| WO-2020127183-A1 | NOVEL POLYMETHOXYFLAVONE COMPOUNDS FOR SKELETAL MUSCLE MODULATION, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2020-06-25 | — | — | WO | claimed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| US-6184246-B1 | Inhibition of cytokine production by polymethoxylated flavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2001-02-06 | — | — | US | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| CN-119745951-A | Application of nine-dragon vine extract in preparation of medicines for treating acute lung injury | 杭州医学院 | 2025-04-04 | — | — | CN | disclosed |
| US-20220054448-A1 | NOVEL POLYMETHOXYFLAVONE COMPOUNDS FOR SKELETAL MUSCLE MODULATION, METHODS AND USES THEREOF | NESTLE SA (CH) | 2022-02-24 | — | — | US | disclosed |
| EP-3897617-A1 | NOVEL POLYMETHOXYFLAVONE COMPOUNDS FOR SKELETAL MUSCLE MODULATION, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113164441-A | Novel polymethoxyflavone compounds for skeletal muscle modulation, methods and uses thereof | 雀巢产品有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| US-6184246-B1 | Inhibition of cytokine production by polymethoxylated flavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2001-02-06 | — | — | US | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220054448-A1 | NOVEL POLYMETHOXYFLAVONE COMPOUNDS FOR SKELETAL MUSCLE MODULATION, METHODS AND USES THEREOF | MYOF, MYLK2, TNNC1 | ABCB1 4821/4885MEN1 4626/4885KMT2A 2094/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | ABCB1 2498/4885MEN1 3867/4885KMT2A 4306/4885 |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | ABCB1 218/4885MEN1 3778/4885KMT2A 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.