Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361887 | 0.78 | ABL1 (0.39) | ABL1KDM4CXIAP | |
| SCHEMBL17361672 | 0.74 | MAOB (0.54) | — | |
| SCHEMBL5327197 | 0.70 | MEN1 (0.36) | MPO | |
| SCHEMBL29648452 | 0.70 | CES1 (0.43) | — | |
| SCHEMBL7749803 | 0.70 | CES1 (0.43) | — | |
| SCHEMBL25333934 | 0.69 | LMNA (0.50) | ARABL1XIAP | |
| SCHEMBL22681671 | 0.69 | NPC1 (0.51) | ARABL1KDM4C | |
| SCHEMBL2317083 | 0.67 | ALDH1A1 (0.49) | MAPK14XIAP | |
| SCHEMBL30758635 | 0.67 | ALDH1A1 (0.49) | MAPK14XIAP | |
| SCHEMBL27784339 | 0.67 | CYP2A6 (0.46) | ARABL1KDM4CEZH2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741749-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3738960-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |