SCHEMBL2268247

SCHEMBL2268247

CCN(CC)C[SiH2]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SIGMAR1 Q99720 2/20 0.38
AOC3 Q16853 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
AGTR1 P30556 1/20 0.35
MC4R P32245 3/20 0.35
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268927 0.78 SIGMAR1 (0.44) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL2267932 0.76 ALDH1A1 (0.42) SIGMAR1AOC3ALDH1A1TSHRTP53
SCHEMBL10652507 0.76 AOC3 (0.45) OPRM1AOC3KDM4EALDH1A1MAPT
SCHEMBL2101245 0.74 DRD3 (0.35) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL311787 0.72
SCHEMBL2102333 0.71 CACNA2D1 (0.34) KCNH2CHRM2HTR1AADRA2ACHRM1
Fluoride SCHEMBL27930946 0.70 TP53 (0.39) ALDH1A1MAPTTSHRMAPK1LMNA
SCHEMBL9621565 0.70 KCNH2 (0.34) KCNH2KDM4EALDH1A1MAPTTSHR
SCHEMBL3682860 0.69 TP53 (0.38) AOC3KDM4EALDH1A1MAPTMAPK1
SCHEMBL2269712 0.69 TP53 (0.38) KCNH2CHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed