Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNKP | Q96T60 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22683130 | 0.65 | HSD17B2 (0.32) | — | |
| SCHEMBL6837036 | 0.52 | CHRM1 (0.56) | — | |
| Bicarbonate SCHEMBL9016429 | 0.52 | LMNA (0.54) | — | |
| SCHEMBL425361 | 0.51 | ALDH1A1 (0.58) | — | |
| SCHEMBL107151 | 0.51 | HPGD (0.48) | — | |
| SCHEMBL8634836 | 0.51 | KMT2A (0.62) | — | |
| SCHEMBL8109262 | 0.51 | LMNA (0.58) | — | |
| SCHEMBL1694742 | 0.51 | LMNA (0.60) | — | |
| SCHEMBL28735249 | 0.51 | LMNA (0.52) | — | |
| SCHEMBL9265958 | 0.50 | LMNA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635579-B1 | SYNTHETIC LETHALITY IN CANCER | UNIV ALBERTA (CA) | 2020-11-25 | — | — | EP | claimed |