Biphenyl

Biphenyl

SCHEMBL226834

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)C=C4)[nH]3.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.54
▸ STAT1 P42224 1/20 0.54
▸ GAA P10253 3/20 0.38
▸ NPC1 O15118 3/20 0.38
▸ RAB9A P51151 3/20 0.38
▸ MAPT P10636 3/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ KDM4E B2RXH2 3/20 0.36
▸ HPGD P15428 3/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ XDH P47989 1/20 0.36
▸ ADORA3 P0DMS8 1/20 0.36
▸ ADORA2A P29274 1/20 0.36
▸ ADORA1 P30542 1/20 0.36
▸ GLA P06280 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ GFER P55789 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ RCE1 Q9Y256 1/20 0.36
▸ MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5367381 0.98 STAT3 (0.53) STAT3STAT1GAANPC1RAB9A
Biphenyl SCHEMBL6265474 0.98 STAT3 (0.53) STAT3STAT1GAANPC1RAB9A
Benzene SCHEMBL29181649 0.91 STAT3 (0.47) STAT3STAT1GAANPC1RAB9A
Benzene SCHEMBL1525265 0.91 STAT3 (0.47) STAT3STAT1GAANPC1RAB9A
Naphthalene SCHEMBL27567972 0.89 STAT3 (0.47) STAT3STAT1GAANPC1RAB9A
Benzene SCHEMBL27320600 0.89 STAT3 (0.46) STAT3STAT1
Benzene SCHEMBL28013127 0.89 STAT3 (0.46) STAT3STAT1
Benzene SCHEMBL28100973 0.89 STAT3 (0.46) STAT3STAT1
Benzene SCHEMBL29118655 0.89 STAT3 (0.46) STAT3STAT1
Benzene SCHEMBL27842146 0.89 STAT3 (0.46) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119454945-A Ultrasonic activated carrier-free nano-drug and preparation method and application thereof 浙江大学 2025-02-18 — — CN claimed
CN-107219280-A A kind of Metalloporphyrins gas sensor element and its preparation method and application 济南大学 2017-09-29 — — CN claimed
JP-6234661-A — — None — — JP disclosed
CN-119219645-B Preparation method of substituted diphenyl porphyrin-2-formaldehyde 湖南科技大学 2026-05-19 — — CN disclosed
CN-119899348-B Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-09-30 — — CN disclosed
CN-119899348-A Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-04-29 — — CN disclosed
CN-119899348-A Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-04-29 — — CN disclosed
CN-119454945-A Ultrasonic activated carrier-free nano-drug and preparation method and application thereof 浙江大学 2025-02-18 — — CN disclosed
CN-119390703-A Intermediate diaryl tetraacenaphthoporphyrin compound, intermediate diaryl tetraacenaphthoporphyrin complex, preparation method and application thereof, pharmaceutical composition and application thereof 上海市皮肤病医院 2025-02-07 — — CN disclosed
CN-119219645-A Preparation method of substituted diphenyl porphyrin-2-formaldehyde 湖南科技大学 2024-12-31 — — CN disclosed
CN-115785889-B Polyurethane adhesive for single-sided adhesive shoes and preparation method thereof 福建华夏蓝新材料科技有限公司 2024-07-05 — — CN disclosed
US-9113535-B2 Fusing porphyrins with polycyclic aromatic hydrocarbons and heterocycles for optoelectronic applications THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2015-08-18 — — US disclosed
CN-103403091-A Additives for curable liquid compositions DURA CHEMICALS INC 2013-11-20 — — CN disclosed
CN-103119046-A Fusing porphyrins with polycyclic aromatic hydrocarbons and heterocycles for optoelectric applications UNIV SOUTHERN CALIFORNIA 2013-05-22 — — CN disclosed
EP-2590983-A2 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRIC APPLICATIONS The University Of Southern California (US) 2013-05-15 — — EP disclosed
WO-2012012117-A2 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRIC APPLICATIONS The University of Southern California USC Stevens Institute for Innovation (US) 2012-01-26 — — WO disclosed
US-20120001155-A1 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-01-05 — — US disclosed
CN-1193793-C Diarylprophin photosensitizer and its preparing process and usage CHINESE ACAD INST CHEMISTRY (CN) 2005-03-23 — — CN disclosed
CN-1382493-A Diarylprophin photosensitizer and its preparing process and usage INST OF CHEMICSTRY CHINESE ACA (CN) 2002-12-04 — — CN disclosed
JP-H06234661-A MRI IMAGING AGENT FOR ARTERIOSCLEROTIC FOCUS AND METHOD FOR IMAGING MRI EIKEN CHEM CO LTD 1994-08-23 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120001155-A1 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS PPOX, HMBS, NONO STAT3 3929/4885STAT1 3896/4885GAA 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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